Activating P300 protein contributes to repair of hippocampal neuronal DNA injuries

Various medications have been developed to treat neurodegenerative disorders, and drugs without significant side effects are gaining widespread interest such disorders.Brain Research Institute of Synergon Consulting in Romania, led by Dragos Cirneci, found that the protein p300, which is a transcription co-activator required for consolidation of memories during specific learning tasks, is at the same time involved in DNA replication and repair, playing a central role in the long-patch pathway of base excision repair.