Wednesday, December 11, 2013

Zinc supplementation and aluminum-induced neurotoxicity

Studies have shown that aluminum neurotoxicity can likely affect learning and memory function, and a diet containing 100-200 mg/kg zinc is adequate for maintaining learning and memory function in rats. Previous findings by Dr. Hao Lu and co-workers from Academy of Military Medical Sciences, China showed that male Wistar rats after treatment with aluminum chloride at a dose of 300 mg/kg daily for 7 weeks exhibited decreased acetylcholinesterase activity and enhanced lipid peroxidation in the cerebrum, appearing to have neurotoxic performance.

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