Scientists at USC have created a mathematical model that explains and predicts the biological process that creates antibody diversity - the phenomenon that keeps us healthy by generating robust immune systems through hypermutation. The work is a collaboration between Myron Goodman, professor of biological sciences and chemistry at the USC Dornsife College of Letters, Arts and Sciences; and Chi Mak, professor of chemistry at USC Dornsife. "To me, it was the holy grail," Goodman said. "We can now predict the motion of a key enzyme that initiates hypermutations in immunoglobulin (Ig) genes...
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