Expert panel diagnosis for diagnostic tests often poorly described, experts often not blinded to test under study

Evaluation of diagnostic studies is often a challenge in diseases that are not defined by a specific test. Assessment of the accuracy of diagnostic tests is essential because they may be used to define who is considered to have a disease and receive treatment for it. However, measuring the accuracy of a diagnostic test requires an accurate gold standard, which defines which patients truly have and do not have the disease. Studies of diseases not defined by a specific test often rely on expert panels to establish the gold standard...