Among critically ill patients, muscle wasting occurs rapidly; more severe among those with multiorgan failure

Zudin A. Puthucheary, M.R.C.P., of University College London, England, and colleagues conducted a study to characterize and evaluate the time course and pathophysiology of acute muscle loss in critical illness. "Survivors of critical illness experience significant skeletal muscle weakness and physical disability, which can persist for at least 5 years...