Tuesday, January 14, 2014

Humans' slow metabolisms explain long life span, study says

Though some individuals may not appreciate their slow metabolisms, a new study suggests that humans and other primates - who burn 50% fewer calories each day than other mammals - have such long lives because of their curiously slow metabolisms.


Publishing their results in the journal Proceedings of the National Academy of Sciences, the international team of scientists says burning fewer calories may also explain why primates grow up so slowly.


Though our pet dogs, cats or hamsters progress to adulthood much faster than we do, reproduce at a faster rate and sadly, die long before we will, humans and other primates - such as apes, monkeys and lemurs - have relatively long childhoods, do not reproduce as frequently and live longer lives.


The researchers note that the slow pace of the primate life has baffled biologists, as the underlying reasons for it were unclear.


In order to better understand, the researchers examined 17 different primate species in zoos and sanctuaries, as well as in the wild, to assess their daily energy expenditure and determine whether their slow pace of life could be attributed to a slow metabolism.


Slow metabolic rate contributes to slow pace of aging


They employed a technique called "doubly labeled water," which is non-invasive and tracks the body's production of carbon dioxide. Using this technique, they were able to measure the calories that the primates burned for a duration of 10 days.


After establishing daily expenditure rates in primates, the team compared them with the rates of other mammals.


According to Herman Pontzer, lead author of the study and anthropologist at Hunter College in New York, the results surprised them:



"Humans, chimpanzees, baboons, and other primates expend only half the calories we'd expect for a mammal. To put that in perspective, a human - even someone with a very physically active lifestyle - would need to run a marathon each day just to approach the average daily energy expenditure of a mammal their size."



The researchers say that this reduction in primates' metabolic rate explains their slow pace of life, and they add that energy expenditure can contribute to aging - as all organisms need energy to grow and reproduce.


"The environmental conditions favoring reduced energy expenditures may hold a key to understanding why primates, including humans, evolved this slower pace of life," says David Raichlen, co-author of the study and anthropologist from the University of Arizona.


Findings may shed light on metabolic diseases and obesity


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