CD8+ T immune cells that are present prior to infection and are specific for influenza virus are associated with reduced severity of influenza-associated illness in people who have been naturally infected. These findings, reported online this week in Nature Medicine, provide support for the development of influenza vaccines aimed at enhancing T cell responses. Vaccines against influenza induce a strong but short-lived antibody response that frequently lacks the ability to neutralize viral strains that are not components of the vaccine...
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