Monday, February 17, 2014

Rituximab may not benefit patients with primary Sjögren syndrome

Rituximab appears to offer no long term benefit to patients with primary Sjögren syndrome (pSS), according to an article published in Annals of Internal Medicine.pSS is a chronic autoimmune disorder characterized by dryness of the eyes and mouth. Up to half of patients have systemic involvement, with fatigue being a symptom associated with significant disability. No systemic treatment has been proved to significantly improve symptoms. Mounting evidence on B cell involvement in pSS suggests that B-cell depletion could be an effective treatment for pSS.

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