Tuesday, October 1, 2013

Mid-life stress linked to dementia risk

A large, long-term study reveals that dealing with stress during middle age may trigger lasting physiological brain changes, increasing the risk of developing dementia later in life.


This finding comes from the Prospective Population Study of Women in Gothenburg, Sweden, which started in 1968 and followed over 800 Swedish women for around 40 years. Results of the study were published online in the journal BMJ Open.


Researchers from the study looked at previous studies showing how stress can cause both structural and functional brain damage, as well as promote inflammation.


They say stress hormones can remain at high levels, long after a traumatic event has passed.


Previous studies looked at the effect of severe psychological stressors in adulthood, such as combat, natural disasters and the Holocaust, and they revealed that mental and physical health were affected decades later.


However, the researchers say that although mild psychosocial stressors are a regular part of life, the "long-term consequences of these more common stressors" have remained unclear.


Data over 40 years shows increased risks


Music practice can sharpen the brain

A new study by researchers at the University of St. Andrews in Scotland concludes that people who practice playing musical instruments have sharper brains because they pick up mistakes in their performance and fix them more quickly than other people.


Writing about their work in a recent issue of the journal Neuropsychologia, psychologist Doctor Ines Jentzsch and colleagues suggest playing music may help guard against mental decline, either through age or disease.


The findings reinforce previous research that links mental ability to playing music.


Dr. Jentzsch, who is a Reader in St. Andrews' School of Psychology and Neuroscience and a keen pianist herself, says:


"Our study shows that even moderate levels of musical activity can benefit brain functioning."


Mental performance of musicians during tasks


For their study, the researchers compared the mental performance of musicians versus non-musicians as they challenged them to complete simple conflict tasks.


There were 36 young adult participants in total, divided into four groups of 8 to 10, according to the number of accumulated hours of practicing a musical instrument over their lifetime (from "high," over 5,000 hours, through "intermediate," 2,000 to 5,000 hours and "low," between 200 and 2,000 hours, to "no," under 200 hours).


The researchers tested each participant's mental ability in a single session that lasted about 2 hours. During the session, they measured the participant's reaction times to the simple mental tasks and also took various physiological measurements.


The simple mental tasks included well-known conflict tests used by psychologists, such as the Stroop test.


In the Stroop test, participants are presented with names of colors depicted in colors that do not necessarily match. For instance, the word "blue" might be shown in the color red, and the word "green" shown in the color blue.


This sets up a conflict in the mind of the participant, who is asked to name the color of each word as it appears before them. The naming of the color is more prone to errors when it does not match the color in which it is presented.


In this study, the researchers were interested, among other things, in reaction times, accuracy and also the amount of post-error adjustment that went on.


More practice, more efficient information processing


Their results show that the amount of musical practice was positively linked to response speed - the more-practiced musicians responded faster than those with little or no musical training, with no loss in accuracy.


"This result suggests that higher levels of musical training might result in more efficient information processing in general [...] and confirms earlier reports indicating a positive link between mental speed and musical ability," write the authors.


However, what this study particularly highlights is that more hours of musical practice were also linked with "better engagement of cognitive control processes," which came through in more efficient error and conflict detection, and reduced levels of post-error interference and post-conflict adjustments.


In other words, the more practice hours musicians had accumulated, the faster their reaction times in completing mental challenges, the better they were able to recognize and correct mistakes, and the less likely they were to go back and adjust their responses when they made mistakes.


This is perhaps not surprising, since practiced musicians learn to be aware of their performance but to not be overly affected by mistakes.


Dr. Jentzsch says their findings could be important because these mental processes are the first to be affected by aging and mental illnesses, like depression:



"The research suggests that musical activity could be used as an effective intervention to slow, stop or even reverse age- or illness-related decline in mental functioning."



Never too late to learn and practice music


Dr. Jentzsch implores policymakers looking for ways to save money in times of hardship to reconsider making cuts in funding for education and arts, and she even recommends increasing spending on music teaching, explaining that:


"Musical activity cannot only immensely enrich our lives, but the associated benefits for our physical and mental functioning could be even more far-reaching than proposed in our and previous research."


She also urges adults who have never played a musical instrument and who say they are too old, to learn to pick one up and start practicing music, because "it's never too late."


Funds from the Wellcome Trust helped finance the study.


Earlier this year, a large-scale review of 400 research papers on the neurochemistry of music also found that playing and listening to music benefits both mental and physical health by improving the immune system and reducing stress.


Written by Catharine Paddock PhD




Copyright: Medical News Today

Not to be reproduced without permission of Medical News Today


Exercising in free time may keep blood pressure healthy

A new study finds that exercising during leisure time is linked to a lower risk for high blood pressure in people who do not do much exercise.


Researchers came to this conclusion after carrying out a meta-analysis that pooled results from 13 studies examining links between exercise and blood pressure.


They found people who did more than 4 hours per week of exercise in their leisure time, as opposed to work time, had a 19% lower risk of high blood pressure, compared with people who did not do much exercise at all.


Writing about their work online this week in the American Heart Association journal Hypertension, the researchers also found no solid link between physical exertion at work and lower risk of high blood pressure.


The American Heart Association defines high blood pressure as having readings at or above 140 mm of mercury for the upper number or 90 or more for the bottom number.


This definition puts around 78 million US adults in the high blood pressure category.


High blood pressure typically has no symptoms and remains undetected and untreated in many people.


Co-author Dr. Bo Xi, a lecturer at the Shandong University School of Public Health in Jinan, China, says current health guidelines that urge people to exercise more for the benefit of their health do not distinguish between physical activity at work and for leisure, but "given the new findings, perhaps they should."


The team pooled data covering nearly 137,000 people in the US, Europe and East Asia who had healthy blood pressure on enrollment to their particular study.


Over a follow-up period ranging from 2 to 45 years, more than 15,600 of the participants developed high blood pressure.


The team found exercising more than 4 hours per week in leisure time was tied to a 19% lower risk for developing high blood pressure, compared with exercising less than 1 hour per week.


The researchers also detected a "dose-response" relationship between recreational physical activity and blood pressure: the more people exercised in their leisure time, the less likely they were to develop high blood pressure.


Even people who only did between 1 and 3 hours per week of leisure-time physical activity had an 11% lower risk of high blood pressure, they found.


However, they found "no significant association" between work-related physical activity and lower risk for high blood pressure.


Leisure exercise different than work-related activity


While the findings may suggest the more recreational exercise you do, the more you protect yourself from developing high blood pressure, Dr. Xi points out they do not prove it. The link may not even be causal.


People who exercise in their leisure time may just have healthier lifestyles, says Dr. Xi.


However, co-author Wei Ma, associate professor at the Shandong University School of Public Health, says high blood pressure is a risk factor for cardiovascular and kidney disease, so it is important to prevent and control it, and nevertheless recommends:


"To try to lower your risk of high blood pressure, you should exercise more in your leisure time."


While the team did not examine the reasons behind their findings, Prof. Ma points out that physical activity at work is different to leisure time exercise.


Work-related activity, such as in farming or industry, may involve heavy lifting, standing for long periods and doing repetitive work.


But leisure time exercise may affect high blood pressure in a number of ways, such as helping retain a healthy weight, improve insuling sensitivity and reduce resistance to flow in blood vessels, Ma adds.


Funds for the study came from the Independent Innovation Foundation of Shandong University, the Research Fund for the Doctoral Program of Higher Education of China and the Foundation for Outstanding Young Scientists in Shandong Province.


Another US study reported earlier this year found that breaking a sweat reduces stroke risk. Those findings revealed that physically inactive people have a 20% higher risk of stroke or TIA (transient ischemic attack or mini-stroke), compared with those who exercise enough to break a sweat four or more times a week.


Written by Catharine Paddock PhD




Copyright: Medical News Today

Not to be reproduced without permission of Medical News Today


IU research attributes high rates of smoking among mentally ill to addiction vulnerability

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